﴿ وَمَا كَانَ لَهُم مِّنْ أَوْلِيَآءَ يَنصُرُونَهُم مِّن دُونِ ٱللَّهِ ۗ وَمَن يُضْلِلِ ٱللَّهُ فَمَا لَهُۥ مِن سَبِيلٍ ﴾

“and will have no protector whatever to succour them against God: for he whom God lets go astray shall find no way [of escape].”

And they have no guardians to help them besides God that is to say other than Him to ward off His chastisement from them and whomever God leads astray has no course of action’ no route to the truth in this world or to Paradise in the Hereafter.