﴿ إِن تَحْرِصْ عَلَىٰ هُدَىٰهُمْ فَإِنَّ ٱللَّهَ لَا يَهْدِى مَن يُضِلُّ ۖ وَمَا لَهُم مِّن نَّٰصِرِينَ ﴾

“[As for those who are bent on denying the truth-] though thou be ever so eager to show them the right way, [know that,] verily, God does not bestow His guidance upon any whom He judges to have gone astray; and such shall have none to succour them [on Resurrection Day].”

(Even if thou (O Muhammad) desirest their right guidance) their profession of Allah's divine Oneness, (still Allah assuredly will not guide) to His religion (him who misleadeth) His created beings from His religion, because this makes him undeserving of His religion. (Such) the disbelievers of Mecca (have no helpers) no one to save them from Allah's chastisement.