﴿ كَلَّا لَا تُطِعْهُ وَٱسْجُدْ وَٱقْتَرِب ۩ ﴾

“Nay, pay thou no heed to him, but prostrate thyself [before God] and draw close [unto Him]!”

(Nay) truly, O Muhammad! (Obey not thou him) i.e. obey not Abu Jahl when he wants you not to pray to your Lord. (But prostrate thyself) to your Lord, (and draw near (unto Allah)) through prostration.